UBE2K and HTT

  • Number of citations of the paper that reports this interaction (PubMedID 8702625)
  • 61
  • Data Source:
  • HPRD (two hybrid, in vitro)

UBE2K

HTT

Description ubiquitin conjugating enzyme E2 K huntingtin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457)
  • Alcohol consumption ( 31358974)
  • Estimated glomerular filtration rate ( 31152163)
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Monobrow ( 27182965)
  • Serum sulfate level ( 27412988)
  • Tuberculosis ( 29036319)
  • Type 2 diabetes ( 30297969)
  • Worry too long after an embarrassing experience ( 29500382)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes 79 interacting genes: AMFR ANAPC11 BARD1 BFAR BIRC7 BIRC8 BRCA1 CASP12 CBLC CDC6 DDI1 DDX58 DIABLO DTX3 DTX3L DZIP3 FZR1 HTT ITCH ITSN1 LRSAM1 MAP3K1 MARCHF3 MARCHF7 MDM2 MID1 MIPOL1 MKRN2 MKRN3 NEDD4L NEDD8 NFKB1 NUB1 PIAS4 PJA1 PRKN PRPF40A PRRG4 RBCK1 RC3H2 REL RING1 RLIM RNF111 RNF114 RNF125 RNF144A RNF167 RNF2 RNF31 RNF32 RNF4 RNF41 RNF5 SENP1 SIAH1 SMURF1 TP53 TRAF7 TRAIP TRIM2 TRIM27 TRIM3 TRIM31 TRIM34 TRIM35 TRIM39 TRIM43 TRIM5 TRIM63 UBA1 UBB UBC UBOX5 UHRF2 USP1 WWP2 ZDHHC17 ZNF384 109 interacting genes: AKT1 AMFR AP2A2 CASP1 CASP3 CASP6 CBS CEP126 CHD3 CHUK CREBBP CRMP1 CTBP1 DLG4 DNALI1 DPPA4 DUSP10 ECH1 EGFR ELP1 ERCC6L ETV4 EVL F8A1 FEZ1 FICD FTL GAPDH GGA2 GIT1 GOLPH3L GPRASP2 GRB2 H2AP H3C10 HAP1 HEYL HIP1 HIP1R HOXC11 HOXC4 HSP90AA1 HSPA8 HYPK IFT20 IKBKB ING5 KAT2B MAGEA3 MAGEB18 MAGEB6 MAP3K10 MBD1 MED21 MED31 MID1 MRFAP1 MRFAP1L1 MTSS1 NCOR1 NUP58 OPTN OSTF1 PACSIN1 PDK2 PEX11B PFN2 PIAS1 PIAS4 PIK3R1 PML PPP2CA PRPF40A PRPF40B PSMC5 RASA1 REST RHEB RNF20 RPS6KB1 SAP30 SETD2 SH3GL3 SH3GLB1 SIN3A SP1 SUMO1 SYMPK TACC1 TAF4 TBP TCERG1 TGM2 TP53 TPR TRAFD1 TRIP10 TTC23 TUBB UBAC1 UBE2E3 UBE2K UTP14A VCP XRCC6 ZDHHC17 ZFYVE19 ZNF451 ZNF655
Entrez ID 3093 3064
HPRD ID 04165 00883
Ensembl ID ENSG00000078140 ENSG00000197386
Uniprot IDs B3KSH4 B4DIZ2 P61086 P42858
PDB IDs 1YLA 2O25 3E46 3F92 3K9O 3K9P 5DFL 6IF1 6JB6 6JB7 2D3X 2LD0 2LD2 3IO4 3IO6 3IOR 3IOT 3IOU 3IOV 3IOW 3LRH 4FE8 4FEB 4FEC 4FED 4RAV 6EZ8 6N8C
Enriched GO Terms of Interacting Partners?
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