HCLS1 and SSBP3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		HCLS1	SSBP3
Description		hematopoietic cell-specific Lyn substrate 1	single stranded DNA binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm Mitochondrion Cytosol Actin Filament Plasma Membrane Postsynaptic Density Lamellipodium Dendrite Site Of Polarized Growth Cortical Actin Cytoskeleton Postsynaptic Membrane	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Transcription Factor Binding Protein Binding SH3 Domain Binding Protein Kinase Binding Actin Filament Binding	Single-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Response To Hormone Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Actin Filament Polymerization Erythrocyte Differentiation Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Macrophage Differentiation Positive Regulation Of Axon Extension Positive Regulation Of Transcription By RNA Polymerase II Neuron Projection Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Cytokine Stimulus Postsynaptic Actin Cytoskeleton Organization Negative Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Actin Cytoskeleton Reorganization	Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development
Pathways
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163 29403010) Body mass index ( 25673413) Food allergy ( 25710614) Menarche (age at onset) ( 27182965) P wave duration ( 28794112) Platelet distribution width ( 27863252) Serum bilirubin levels in metabolic syndrome ( 30621171) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
Interacting Genes		23 interacting genes: ACTA1 ACTR2 ACTR3 BLZF1 CASP3 CD79A CSNK2A1 FGR GRB2 HAX1 HS1BP3 IKBKG LYN LZTR1 MAP4K1 QKI SH2D4A SSBP3 SYK TERF1 TRIM29 WAS ZBTB25	17 interacting genes: ANKEF1 APP ARNT2 CLK1 EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		3059	23648
HPRD ID		03199	09578
Ensembl ID		ENSG00000180353	ENSG00000157216
Uniprot IDs		P14317	Q9BWW4 Q9NW25
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?