TNPO2 and KLHL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TNPO2	KLHL2
Description		transportin 2	kelch like family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Nuclear Import Signal Receptor Activity	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	Protein Import Into Nucleus	Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		18 interacting genes: A1CF APIP C1orf94 CAMK2D CRYAB ELAVL1 EXOC5 KLHL2 NME1 NUP98 NXF1 PIK3CD PNMA5 RAN RPL4 TCL1B TERF1 TRMT1	15 interacting genes: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114
Entrez ID		30000	11275
HPRD ID		04301	09311
Ensembl ID		ENSG00000105576	ENSG00000109466
Uniprot IDs		A0A024R7F7 O14787 Q05D48 Q4LE60	B4DFZ5 E9PEX9 O95198
PDB IDs			2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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