GYPC and PDIA3

Number of citations of the paper that reports this interaction (PubMedID 9153243)
17

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		GYPC	PDIA3
Description		glycophorin C (Gerbich blood group)	protein disulfide isomerase family A member 3
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton	Extracellular Space Cell Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Focal Adhesion Cell Surface Melanosome MHC Class I Peptide Loading Complex Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Cysteine-type Endopeptidase Activity Phospholipase C Activity Protein Binding Disulfide Oxidoreductase Activity Peptide Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process	Leukocyte Migration	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Protein Folding Proteolysis Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Oxidation-reduction Process Cellular Response To Interleukin-7 Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Cell surface interactions at the vascular wall	ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Zinc Copper
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)	Blood protein levels ( 30072576) Lead levels ( 26025379)
Interacting Genes		3 interacting genes: EPB41 MPP1 PDIA3	20 interacting genes: APP BACE1 CALR CANX ERO1A ERP27 ESR1 FBLN5 GYPC HLA-A IFNG LGALS9 MDM2 MTNR1B SLC12A3 SLC2A1 STAT3 SUMO4 TAP1 UBE3A
Entrez ID		2995	2923
HPRD ID		00193	03625
Ensembl ID		ENSG00000136732	ENSG00000167004
Uniprot IDs		P04921	P30101 V9HVY3
PDB IDs		2EJY	2ALB 2DMM 2H8L 3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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