GYPC and EPB41

Number of citations of the paper that reports this interaction (PubMedID 11423550)
14

Data Source:
HPRD (in vitro, in vivo)

		GYPC	EPB41
Description		glycophorin C (Gerbich blood group)	erythrocyte membrane protein band 4.1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton	Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Nuclear Body Cell Junction Cortical Cytoskeleton Protein-containing Complex Intercellular Bridge Mitotic Spindle Cell Cortex Region
	Molecular Function	Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Protein C-terminus Binding Spectrin Binding Protein N-terminus Binding Phosphoprotein Binding
	Biological Process	Leukocyte Migration	Cell Cycle Regulation Of Cell Shape Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Positive Regulation Of Protein Binding Cell Division Regulation Of Calcium Ion Transport Protein-containing Complex Assembly Regulation Of Intestinal Absorption Positive Regulation Of Protein Localization To Cell Cortex
Pathways		Cell surface interactions at the vascular wall	Neurexins and neuroligins
Drugs
Diseases			Hereditary elliptocytosis (HE)
GWAS		Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Tourette syndrome ( 30818990)
Interacting Genes		3 interacting genes: EPB41 MPP1 PDIA3	39 interacting genes: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10
Entrez ID		2995	2035
HPRD ID		00193	00558
Ensembl ID		ENSG00000136732	ENSG00000159023
Uniprot IDs		P04921	A0A2R8Y5G2 A0A2R8Y5Z6 A0A2R8Y6D0 A0A2R8Y7Y3 A0A2U3TZH6 P11171 Q1WWM3 Q29RX4 Q59F12
PDB IDs		2EJY	1GG3 2RQ1 3QIJ
Enriched GO Terms of Interacting Partners?
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