SYNE4 and KTN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SYNE4	KTN1
Description		spectrin repeat containing nuclear envelope family member 4	kinectin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	RNA Binding Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Microtubule-based Movement Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)
Interacting Genes		51 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	14 interacting genes: BNIP3 CDC42 CLEC7A EEF1D IKBKE KIF5B MEOX2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA SYNE4
Entrez ID		163183	3895
HPRD ID		08776	02661
Ensembl ID		ENSG00000181392	ENSG00000126777
Uniprot IDs		Q8N205	A0A024R663 Q86UP2
PDB IDs
Enriched GO Terms of Interacting Partners?
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