SYNE4 and CLDN7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SYNE4	CLDN7
Description		spectrin repeat containing nuclear envelope family member 4	claudin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Protein Domain Specific Binding Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Proliferation Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Protein Complex Assembly Negative Regulation Of Apoptotic Process Response To Ethanol Positive Regulation Of Cell Motility
Pathways			Tight junction interactions
Drugs
Diseases
GWAS			Birth weight ( 31043758 27680694) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Multiple sclerosis ( 31604244) Offspring birth weight ( 31043758)
Interacting Genes		51 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250	7 interacting genes: AQP2 EPCAM GLP1R HGD RHOXF2 SYNE4 TJP1
Entrez ID		163183	1366
HPRD ID		08776	07633
Ensembl ID		ENSG00000181392	ENSG00000181885
Uniprot IDs		Q8N205	A0A384ME58 F5H496 O95471
PDB IDs
Enriched GO Terms of Interacting Partners?
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