USP25 and ZNF426

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		USP25	ZNF426
Description		ubiquitin specific peptidase 25	zinc finger protein 426
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Cytosol	Nucleus
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity Ubiquitin-like Protein-specific Protease Activity Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding ATPase Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway	Regulation Of Transcription, DNA-templated
Pathways		Ub-specific processing proteases	Generic Transcription Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 25489960) Metabolite levels ( 23823483) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Panic disorder ( 19165232) Parkinson's disease ( 21738487) QRS complex (12-leadsum) ( 27659466) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		16 interacting genes: ACTA1 FLNC GAPDH MAGEB4 MT2A RAD23A SENP1 SKIL SUMO1 SUMO2 SUMO3 SYK TNKS UBC UBE2I ZNF426	15 interacting genes: CALCOCO2 CCDC85B CEP70 CIB3 EFEMP2 GLRX3 KRTAP4-12 LPXN LZTS2 MDFI MPPE1 MTUS2 NINL TSGA10 USP25
Entrez ID		29761	79088
HPRD ID		05296	15787
Ensembl ID		ENSG00000155313	ENSG00000130818
Uniprot IDs		Q9UHP3	A0A024R7D7 K7EME3 K7ER43 Q59EH4 Q9BUY5
PDB IDs		2MUX 5GP7 5O71 6H4J 6H4K 6HEL 6HEM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?