CHMP4C and CC2D1A

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
HPRD (two hybrid)

		CHMP4C	CC2D1A
Description		charged multivesicular body protein 4C	coiled-coil and C2 domain containing 1A
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body	Fibrillar Center Nucleus Microtubule Organizing Center Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Cadherin Binding
	Biological Process	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	4 interacting genes: CDC37 CHMP4A CHMP4C LRP1
Entrez ID		92421	54862
HPRD ID		18135	08616
Ensembl ID		ENSG00000164695	ENSG00000132024
Uniprot IDs		Q96CF2	Q6P1N0
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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