CHMP4C and USP54

Number of citations of the paper that reports this interaction (PubMedID 19302785)
8

Data Source:
BioGRID (pull down)

		CHMP4C	USP54
Description		charged multivesicular body protein 4C	ubiquitin specific peptidase 54
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Cell Cytosol Midbody Late Endosome Membrane Flemming Body
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity
	Biological Process	Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Protein Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	21 interacting genes: ARID5B ATN1 ATXN1 CDK19 CFAP70 CHMP1B CHMP2A CHMP2B CHMP4C COMTD1 EIF4E2 FAM149B1 FUT11 HK1 MSS51 MSX2 NXT2 PLCD1 SAMD8 TTYH1 UBC
Entrez ID		92421	159195
HPRD ID		18135	15641
Ensembl ID		ENSG00000164695	ENSG00000166348
Uniprot IDs		Q96CF2	B7Z7X1 Q70EL1
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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