ANK3 and SCN2A

  • Number of citations of the paper that reports this interaction (PubMedID 12036953)
  • 20
  • Data Source:
  • HPRD (in vivo)

ANK3

SCN2A

Description ankyrin 3 sodium voltage-gated channel alpha subunit 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Bipolar disorder ( 22182935 21926972 18711365 24618891 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Chronotype ( 30696823)
  • Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Heel bone mineral density ( 30598549)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
  • Psychotic experience ( 31553412)
  • Schizophrenia ( 20185149)
  • Third ventricle volume ( 31530798)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
Interacting Genes 17 interacting genes: FADD FAS GABARAP HOOK1 KCNC1 MAP1LC3A MAP1LC3C MAPK6 PIK3R1 PLEC SCN1B SCN2A SCNN1B SMAD2 SMAD3 SPTBN4 SRPK2 5 interacting genes: ANK3 ARHGEF10L MPP3 RNF130 SCN4B
Entrez ID 288 6326
HPRD ID 02715 03133
Ensembl ID ENSG00000151150 ENSG00000136531
Uniprot IDs Q12955 Q8NAK2 Q99250
PDB IDs 4O6X 2KAV 4JPZ 4RLY 6BUT 6J8E
Enriched GO Terms of Interacting Partners?
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