ANK3 and HOOK1

Number of citations of the paper that reports this interaction (PubMedID 15823567)
11

Data Source:
HPRD (in vitro, two hybrid)

		ANK3	HOOK1
Description		ankyrin 3	hook microtubule tethering protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cell Lysosome Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Bicellular Tight Junction Basal Plasma Membrane Cell Surface Intercalated Disc Spectrin-associated Cytoskeleton Membrane Basolateral Plasma Membrane Lateral Plasma Membrane Sarcoplasmic Reticulum Z Disc T-tubule Dendrite Neuromuscular Junction Node Of Ranvier Sarcolemma Neuron Projection Costamere Axon Initial Segment Postsynaptic Membrane	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Spectrin Binding Protein Binding, Bridging Ion Channel Binding Cadherin Binding	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding
	Biological Process	Mitotic Cytokinesis ER To Golgi Vesicle-mediated Transport Plasma Membrane Organization Cytoskeletal Anchoring At Plasma Membrane Signal Transduction Axonogenesis Neuromuscular Junction Development Positive Regulation Of Gene Expression Positive Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Sodium Ion Transport Magnesium Ion Homeostasis Neuronal Action Potential Positive Regulation Of Homotypic Cell-cell Adhesion Golgi To Plasma Membrane Protein Transport Regulation Of Potassium Ion Transport Establishment Of Protein Localization Positive Regulation Of Membrane Potential Cellular Response To Magnesium Ion Membrane Assembly Protein Localization To Plasma Membrane Maintenance Of Protein Location In Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Protein Localization To Axon Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Cation Channel Activity	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly
Pathways		Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833) Bipolar disorder ( 22182935 21926972 18711365 24618891 31043756 28072414 20351715) Bipolar disorder or major depressive disorder ( 20351715) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Height ( 31562340) Metabolite levels ( 23823483) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457) Psychotic experience ( 31553412) Schizophrenia ( 20185149) Third ventricle volume ( 31530798) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: FADD FAS GABARAP HOOK1 KCNC1 MAP1LC3A MAP1LC3C MAPK6 PIK3R1 PLEC SCN1B SCN2A SCNN1B SMAD2 SMAD3 SPTBN4 SRPK2	22 interacting genes: AKTIP ANK3 CDC5L CDK4 ERI3 FAM160A2 HOOK2 HOOK3 LMO2 MRPL37 MYSM1 S100A7 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785
Entrez ID		288	51361
HPRD ID		02715	07428
Ensembl ID		ENSG00000151150	ENSG00000134709
Uniprot IDs		Q12955 Q8NAK2	Q9UJC3
PDB IDs		4O6X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?