ANK3 and MAPK6

  • Number of citations of the paper that reports this interaction (PubMedID 20936779)
  • 85
  • Data Source:
  • BioGRID (two hybrid)

ANK3

MAPK6

Description ankyrin 3 mitogen-activated protein kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Bipolar disorder ( 22182935 21926972 18711365 24618891 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Chronotype ( 30696823)
  • Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Heel bone mineral density ( 30598549)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
  • Psychotic experience ( 31553412)
  • Schizophrenia ( 20185149)
  • Third ventricle volume ( 31530798)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes 17 interacting genes: FADD FAS GABARAP HOOK1 KCNC1 MAP1LC3A MAP1LC3C MAPK6 PIK3R1 PLEC SCN1B SCN2A SCNN1B SMAD2 SMAD3 SPTBN4 SRPK2 166 interacting genes: ACTG1 ACTR1B AMPH ANAPC5 ANK3 APBA2 ARHGDIA ARPC3 ATG9A ATP5PF BAG6 BARX1 BBS10 CA1 CA12 CALR CASP6 CCND3 CCT3 CDH13 CERS1 CFAP298 CFL1 CNTN1 CNTRL COPS6 CSE1L CYRIB CYTH2 DBN1 DCTN2 DDOST DDR1 DGKZ DKC1 DNAJC28 DPPA4 DST EDF1 EEF1A2 EIF1 EIF3C EIF4A1 ELOF1 EMD FBXL16 FOXO3 FXYD3 GALNT7 GATA1 GLRX3 GORASP1 GPX1 HACL1 HAUS2 HDAC11 HIP1 HNRNPA0 HNRNPD HNRNPH3 HSP90AB1 HSP90B1 HSPD1 IDH3B INS ITGB3BP ITSN1 JUNB KDSR KLC1 KNSTRN LPXN MAP3K12 MAP3K7 MAPKAPK5 MASP1 MBIP MBOAT7 MCM3 MDK METTL17 METTL2A MGAT1 MIPEP MOK MON1A MTG2 MYBL2 MYOZ3 MZB1 NAT9 NAXE NDUFS6 NECTIN2 NELFB NOL4 NRXN2 NUDT5 OSTF1 PDCD6IP PDLIM1 PHACTR3 PHC2 PHGDH PIH1D1 PLEKHM1 PLSCR1 PPBP PPP1R7 PPP2R1A PRKAB1 PRKAR1A PRKCB PRPF38A PSAT1 PSIP1 PTPMT1 RAB2A RAB31 RACK1 RANBP9 RAP1GAP RARA RBL1 RGS19 RPL10 RRP7A SEPTIN3 SEPTIN5 SERPINA4 SHC1 SLC20A1 SLC41A3 SMAD6 SMS SNAPC4 SNW1 SOCS3 SPG7 SPRR2D SPTAN1 SRSF5 STX7 TCF12 TDP2 THAP4 TPI1 TTK TUBA1A UBA52 UBE2L3 URB1 USP20 VPS26C WDR26 WDR34 WFS1 WWC1 XPO1 ZNF133 ZNF205 ZNF331 ZNF579 ZNF600 ZNF671 ZNF775
Entrez ID 288 5597
HPRD ID 02715 04213
Ensembl ID ENSG00000151150 ENSG00000069956
Uniprot IDs Q12955 Q8NAK2 Q16659
PDB IDs 4O6X 2I6L
Enriched GO Terms of Interacting Partners?
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