PRPF31 and TADA2A

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		PRPF31	TADA2A
Description		pre-mRNA processing factor 31	transcriptional adaptor 2A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex	PCAF Complex Nucleus Chromosome SAGA-type Complex
	Molecular Function	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Ribonucleoprotein Complex Binding SnRNP Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	HATs acetylate histones
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)	Ovarian cancer ( 23535730)
Interacting Genes		76 interacting genes: C1QTNF1 CALCOCO2 CBY2 CCDC136 CCDC33 CCDC57 CCNDBP1 CDCA7L CEP70 DVL2 EFEMP2 FANCA FANCC FASTK GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 LZTS2 MDFI MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NDUFB9 NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PSTPIP1 RACK1 RBM25 RBM4 RBMX RBMY1A1 RBMY1F RINT1 SIAH1 SNRNP200 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM27 TRIM41 TSGA10 USP15 ZFP64 ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF587	39 interacting genes: ARNT2 C1orf109 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 MAGOH MCPH1 MFAP1 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564 ZNF688
Entrez ID		26121	6871
HPRD ID		05917	03784
Ensembl ID		ENSG00000105618	ENSG00000276234
Uniprot IDs		Q8WWY3	A0A024R0Y4 A0A087WWR4 B3KU13 O75478
PDB IDs		2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9	1X41
Enriched GO Terms of Interacting Partners?
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