TADA2A and TCF3

Number of citations of the paper that reports this interaction (PubMedID 23044487)
16

Data Source:
BioGRID (pull down)

		TADA2A	TCF3
Description		transcriptional adaptor 2A	transcription factor 3
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GO Annotations	Cellular Component	PCAF Complex Nucleus Chromosome SAGA-type Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Enhancer Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding Vitamin D Response Element Binding E-box Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II B Cell Lineage Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated B Cell Differentiation Immunoglobulin V(D)J Recombination Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Muscle Cell Differentiation Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		HATs acetylate histones	Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
GWAS		Ovarian cancer ( 23535730)	Hodgkin's lymphoma ( 29196614 24920014) Objective response to lithium treatment ( 26503763)
Interacting Genes		39 interacting genes: ARNT2 C1orf109 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 MAGOH MCPH1 MFAP1 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564 ZNF688	66 interacting genes: AEBP1 ASCL3 AURKA BHLHA15 BHLHE40 CALM1 CALM3 CBFA2T3 CREBBP CTNNB1 DACH1 DAXX ELK3 EP300 FERD3L GLIS1 HAND1 HAND2 HOXA1 ID1 ID2 ID3 KAT2A KAT2B LMX1A LMX1B LYL1 MAPK1 MAPK3 MAPKAPK2 MAPKAPK3 MDFI MEN1 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 NEUROD1 NHLH1 NSD3 PARP1 PDX1 PSMD4 PSMD9 RALGAPA1 RPL37 RUNX1T1 SCX SKP2 SRF SUPT3H TADA2A TAL1 TAL2 TCAF1 TCF12 TCF21 TCF4 TFPT TLE1 TRRAP TWIST1 UBE2I USF1
Entrez ID		6871	6929
HPRD ID		03784	00918
Ensembl ID		ENSG00000276234	ENSG00000071564
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	A0A0A0MRB7 P15923 X6REB3
PDB IDs		1X41	1HLH 2MH0 2YPA 2YPB 3U5V 6MGN
Enriched GO Terms of Interacting Partners?
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