RAD54B and ATPAF2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		RAD54B	ATPAF2
Description		RAD54 homolog B	ATP synthase mitochondrial F1 complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Cytosol Nuclear Speck
	Molecular Function	DNA Binding DNA Helicase Activity RNA Helicase Activity Protein Binding ATP Binding DNA Translocase Activity	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination DNA Duplex Unwinding	Proton-transporting ATP Synthase Complex Assembly
Pathways
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Nonsyndromic cleft lip with cleft palate ( 28232668)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		27 interacting genes: ANKRD36BP1 ATPAF2 CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 LNX1 MDM4 MYO15B NDUFB9 NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SUMO1 TCEANC TRAPPC6A UBE2I WRN ZNF580	24 interacting genes: APP ATP5F1A ATP5F1B BEGAIN CFAP206 DDIT3 EBF1 EWSR1 IKZF3 KRT40 LNX1 LRRFIP2 LZTS2 MAGEA6 PAK5 PKP4 PRDM14 RAD54B REL RPIA SORBS2 TP53BP2 TRIM23 TRIM27
Entrez ID		25788	91647
HPRD ID		05049	10599
Ensembl ID		ENSG00000197275	ENSG00000171953
Uniprot IDs		A0A087X0H2 O95073 Q9Y620	Q8N5M1
PDB IDs
Enriched GO Terms of Interacting Partners?
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