GAD1 and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		GAD1	AGTRAP
Description		glutamate decarboxylase 1	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Vesicle Membrane Axon Terminus Presynaptic Active Zone Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding Protein N-terminus Binding	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Glutamate Catabolic Process Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Gamma-aminobutyric Acid Biosynthetic Process Protein-pyridoxal-5-phosphate Linkage Social Behavior Locomotory Exploration Behavior Response To Drug	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways		GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling	Signaling by BRAF and RAF fusions
Drugs		Pyridoxal Phosphate Pyridoxal Phosphate Pyridoxal Phosphate Glutamic Acid
Diseases		Cerebral palsy
GWAS		Menopause (age at onset) ( 26414677)	Systolic blood pressure ( 19430483)
Interacting Genes		15 interacting genes: AGTRAP CMTM5 GAD2 HAAO KRT31 KRT40 KRTAP3-2 MAL2 PPP2CA PPP2CB PRKACA PRKCE STK3 TRIM23 TRIP6	79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391
Entrez ID		2571	57085
HPRD ID		12011	16379
Ensembl ID		ENSG00000128683	ENSG00000177674
Uniprot IDs		A0A0S2Z3V5 Q8IVA8 Q99259	Q6RW13
PDB IDs		2OKJ 3VP6
Enriched GO Terms of Interacting Partners?
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