CBX7 and PCGF6

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		CBX7	PCGF6
Description		chromobox 7	polycomb group ring finger 6
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol PcG Protein Complex PRC1 Complex	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Inactivation Of X Chromosome By Genetic Imprinting Negative Regulation Of G0 To G1 Transition
Pathways			Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lymphocyte counts ( 27863252) Menarche (age at onset) ( 25231870) Multiple myeloma ( 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) White blood cell count ( 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		7 interacting genes: B3GNT5 H3-4 PCGF1 PCGF5 PCGF6 RING1 SUV39H2	22 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 UBE2D3 UBE2U USP2 USP21
Entrez ID		23492	84108
HPRD ID		12234	07427
Ensembl ID		ENSG00000100307	ENSG00000156374
Uniprot IDs		A0A024R1Q2 B0QYP2 O95931 Q4PNR6	Q9BYE7
PDB IDs		2K1B 2L12 2L1B 3GS2 4MN3 5EPJ	2DJB
Enriched GO Terms of Interacting Partners?
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