KIFAP3 and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
65

Data Source:
HPRD (in vivo)

		KIFAP3	RPGR
Description		kinesin associated protein 3	retinitis pigmentosa GTPase regulator
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Cell Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Cilium Axoneme Microtubule Cytoskeleton Kinesin II Complex Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Periciliary Membrane Compartment	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Protein Binding Kinesin Binding Protein Phosphatase Binding Intraciliary Transport Particle B Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Process Microtubule-based Movement Signal Transduction Negative Regulation Of Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Apoptotic Process Cilium Organization Positive Regulation Of Calcium-dependent Cell-cell Adhesion Protein-containing Complex Assembly Plus-end-directed Vesicle Transport Along Microtubule	Intracellular Protein Transport Visual Perception Intraciliary Transport Response To Stimulus Cilium Assembly
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases			Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS		Adverse response to drug ( 30420678) Amyotrophic lateral sclerosis ( 19451621) Atrial fibrillation ( 28416818) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		27 interacting genes: APC AR CCSER2 DHX37 DISC1 GTSE1 KIF3B MAP3K10 MAP3K11 MARK2 MEST MINK1 NAA10 NAV1 NCF2 NIPSNAP3A NUDT21 PARD6G PEX19 PRNP RAP1GDS1 RBFOX1 RBM14 RPGR SMC3 SRC TOR1AIP1	14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE
Entrez ID		22920	6103
HPRD ID		03499	02425
Ensembl ID		ENSG00000075945	ENSG00000156313
Uniprot IDs		Q92845	Q92834
PDB IDs			4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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