RPGR and KIF3A

Number of citations of the paper that reports this interaction (PubMedID 16043481)
65

Data Source:
HPRD (in vivo)

		RPGR	KIF3A
Description		retinitis pigmentosa GTPase regulator	kinesin family member 3A
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Cell Centrosome Centriole Cytosol Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Kinesin II Complex Extracellular Exosome Ciliary Tip Axon Cytoplasm
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rab GTPase Binding Protein Phosphatase Binding Spectrin Binding
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Response To Stimulus Cilium Assembly	Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Organization Microtubule-based Movement Axon Guidance Anterograde Axonal Transport Centriole-centriole Cohesion Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Protein Localization To Cell Junction
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Hedgehog 'off' state Intraflagellar transport Activation of SMO Activation of SMO COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 25574825 22197932 26482879) Atopic march ( 26542096) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mosquito bite size ( 28199695)
Interacting Genes		14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	14 interacting genes: APP DISC1 GRB2 KIF3B KIF3C LIG4 MAP3K10 MAP3K11 NEK1 PLEKHA5 PPP1R15A RPGR TRIM14 VHL
Entrez ID		6103	11127
HPRD ID		02425	05250
Ensembl ID		ENSG00000156313	ENSG00000131437
Uniprot IDs		Q92834	B4DHG8 E9PES4 J3KPF9 Q05CT3 Q9Y496
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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