MON1B and RABGEF1

Number of citations of the paper that reports this interaction (PubMedID 20434987)
217

Data Source:
BioGRID (pull down)

		MON1B	RABGEF1
Description		MON1 homolog B, secretory trafficking associated	RAB guanine nucleotide exchange factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mon1-Ccz1 Complex	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome
	Molecular Function	Protein Binding	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Protein Targeting To Vacuole Early Viral Transcription Late Viral Transcription	Protein Targeting To Membrane Endocytosis
Pathways		RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811) Immune response to measles-mumps-rubella vaccine ( 24811271) Metabolite levels ( 23823483) Multisite chronic pain ( 31194737) Number of sexual partners ( 30643258)	Aortic root size ( 21223598) Central corneal thickness ( 29760442)
Interacting Genes		6 interacting genes: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41	29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C
Entrez ID		22879	27342
HPRD ID		12342	11477
Ensembl ID		ENSG00000103111	ENSG00000154710
Uniprot IDs		B4DKA0 E7EW32 Q6ZR87 Q7L1V2	A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41
PDB IDs			1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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