RABGEF1 and TRIM54

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RABGEF1	TRIM54
Description		RAB guanine nucleotide exchange factor 1	tripartite motif containing 54
Image
GO Annotations	Cellular Component	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome	Microtubule Microtubule Associated Complex Z Disc
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding	Protein Binding Microtubule Binding Zinc Ion Binding
	Biological Process	Protein Targeting To Membrane Endocytosis	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organism Development Cell Differentiation
Pathways		TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Central corneal thickness ( 29760442)
Interacting Genes		29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C	132 interacting genes: ADCY4 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 C2CD6 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC87 CDK18 CDKN1A CENPX CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DEUP1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ELOA ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 HSPB1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 NTAQ1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM TBC1D22B TCEA2 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D2 UBE2D3 UBE2E3 UBE2I UBE2N UBE2U UBE2V2 UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587
Entrez ID		27342	57159
HPRD ID		11477	05928
Ensembl ID		ENSG00000154710	ENSG00000138100
Uniprot IDs		A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41	Q9BYV2
PDB IDs		1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U	3Q1D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?