RABGEF1 and AP1G1

Number of citations of the paper that reports this interaction (PubMedID 15143060)
14

Data Source:
HPRD (two hybrid)

		RABGEF1	AP1G1
Description		RAB guanine nucleotide exchange factor 1	adaptor related protein complex 1 subunit gamma 1
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GO Annotations	Cellular Component	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding	Protein Binding Rab GTPase Binding Kinesin Binding GTP-dependent Protein Binding
	Biological Process	Protein Targeting To Membrane Endocytosis	Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport
Pathways		TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Central corneal thickness ( 29760442)	General cognitive ability ( 29844566) Post bronchodilator FEV1 ( 26634245) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C	24 interacting genes: AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CLINT1 CLTC DNER EPS15 KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SPTB SYNRG SYP UBL7 UPF1 ZNF512B
Entrez ID		27342	164
HPRD ID		11477	04637
Ensembl ID		ENSG00000154710	ENSG00000166747
Uniprot IDs		A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41	A0A140VJE7 O43747 Q8IY97
PDB IDs		1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U	1IU1
Enriched GO Terms of Interacting Partners?
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