MON1B and VPS41

Number of citations of the paper that reports this interaction (PubMedID 20434987)
217

Data Source:
BioGRID (pull down)

		MON1B	VPS41
Description		MON1 homolog B, secretory trafficking associated	VPS41 subunit of HOPS complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mon1-Ccz1 Complex	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Protein Targeting To Vacuole Early Viral Transcription Late Viral Transcription	Protein Targeting To Vacuole Autophagy Endosome To Lysosome Transport Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Regulated Exocytosis Late Endosome To Lysosome Transport
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811) Immune response to measles-mumps-rubella vaccine ( 24811271) Metabolite levels ( 23823483) Multisite chronic pain ( 31194737) Number of sexual partners ( 30643258)	Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		6 interacting genes: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41	12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B
Entrez ID		22879	27072
HPRD ID		12342	10402
Ensembl ID		ENSG00000103111	ENSG00000006715
Uniprot IDs		B4DKA0 E7EW32 Q6ZR87 Q7L1V2	P49754
PDB IDs
Enriched GO Terms of Interacting Partners?
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