IKZF2 and LONRF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		IKZF2	LONRF1
Description		IKAROS family zinc finger 2	LON peptidase N-terminal domain and ring finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Cytosol
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Biological_process Positive Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Eosinophil counts ( 29403010 19198610 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31451708) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Selective IgA deficiency ( 27723758) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338) Systemic sclerosis ( 29293537)	Colorectal cancer (diet interaction) ( 24743840)
Interacting Genes		8 interacting genes: AQP1 CTBP1 CTBP2 HDAC4 IKZF1 IKZF4 IKZF5 LONRF1	33 interacting genes: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CRX EFHC2 GORASP1 GORASP2 HSPB1 IHO1 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 NTAQ1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 XIAP
Entrez ID		22807	91694
HPRD ID		05872	08674
Ensembl ID		ENSG00000030419	ENSG00000154359
Uniprot IDs		A0A024R3Z4 Q9UKS7	Q17RB8
PDB IDs
Enriched GO Terms of Interacting Partners?
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