FANCC and FANCA

Number of citations of the paper that reports this interaction (PubMedID 10373536)
46

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		FANCC	FANCA
Description		FA complementation group C	FA complementation group A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance	DNA Repair Male Meiotic Nuclear Division Male Gonad Development Female Gonad Development Interstrand Cross-link Repair Regulation Of Cell Proliferation Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Protein-containing Complex Assembly Regulation Of CD40 Signaling Pathway
Pathways		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes	Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Birth weight ( 31043758) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)	Hair morphology traits ( 30166351) Homocysteine levels ( 23824729) Intraocular pressure ( 29617998 29785010 31959993 30054594) Low tan response ( 29739929) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Skin pigmentation traits ( 30166351)
Interacting Genes		34 interacting genes: AZIN1 CAPN10 CCNA2 CDK1 CTBP1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 MEOX2 MT-ATP6 POR PRDX3 PRPF31 RPL18 RPS3A SPTA1 SPTAN1 STAT1 STMN1 STMN2 TCERG1 USP14 ZBTB32	48 interacting genes: AKT1 ALDOA ATP5F1B ATR AURKA AZIN1 BRCA1 CAPN1 CCT3 CD79A CDK1 CENPE DAXX DDX39B DNAJB1 DUS4L ENO1 FANCC FANCE FANCF FANCG GNB2 HES1 HPRT1 HSP90AA1 IFIT3 IKBKB KRT1 LIPG MKNK1 MX1 NAMPT NUB1 PRKAA1 PRPF31 PSMA5 RPL18 SGK1 SMARCA4 SMARCC1 SMARCD3 SNX5 SPTAN1 TAF10 TCERG1 TCP1 TPT1 ZNF24
Entrez ID		2176	2175
HPRD ID		01967	06186
Ensembl ID		ENSG00000158169	ENSG00000187741
Uniprot IDs		A0A024R9N2 A0A087WW44 B4E3W2 Q00597	O15360
PDB IDs
Enriched GO Terms of Interacting Partners?
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