FANCC and FANCD2

Number of citations of the paper that reports this interaction (PubMedID 11751423)
13

Data Source:
HPRD (in vivo)

		FANCC	FANCD2
Description		FA complementation group C	FA complementation group D2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex	Condensed Chromosome Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Body
	Molecular Function	Protein Binding	Protein Binding DNA Polymerase Binding
	Biological Process	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance	Synapsis Gamete Generation Response To Gamma Radiation Intra-S DNA Damage Checkpoint Cellular Response To Oxidative Stress Interstrand Cross-link Repair Regulation Of Regulatory T Cell Differentiation Brain Morphogenesis Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Neuronal Stem Cell Population Maintenance Double-strand Break Repair Involved In Meiotic Recombination Regulation Of CD40 Signaling Pathway
Pathways		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Birth weight ( 31043758) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)	Alzheimer's disease ( 24755620) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		34 interacting genes: AZIN1 CAPN10 CCNA2 CDK1 CTBP1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 MEOX2 MT-ATP6 POR PRDX3 PRPF31 RPL18 RPS3A SPTA1 SPTAN1 STAT1 STMN1 STMN2 TCERG1 USP14 ZBTB32	28 interacting genes: ATM ATR BLM BRCA1 BRCA2 BRIP1 FANCC FANCE FANCI FANCL H2AC4 H2BC3 H3C1 H4C1 MEN1 MRE11 NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB UBE2T UHRF1 UHRF2 USP1
Entrez ID		2176	2177
HPRD ID		01967	01968
Ensembl ID		ENSG00000158169	ENSG00000144554
Uniprot IDs		A0A024R9N2 A0A087WW44 B4E3W2 Q00597	Q9BXW9
PDB IDs
Enriched GO Terms of Interacting Partners?
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