FANCA and CCT3

Number of citations of the paper that reports this interaction (PubMedID 14499622)
12

Data Source:
BioGRID (two hybrid)

		FANCA	CCT3
Description		FA complementation group A	chaperonin containing TCP1 subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex	Zona Pellucida Receptor Complex Cytosol Chaperonin-containing T-complex Cytoskeleton Microtubule Plasma Membrane Cell Body Extracellular Exosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding ATP Binding Unfolded Protein Binding
	Biological Process	DNA Repair Male Meiotic Nuclear Division Male Gonad Development Female Gonad Development Interstrand Cross-link Repair Regulation Of Cell Proliferation Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Protein-containing Complex Assembly Regulation Of CD40 Signaling Pathway	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Pore Complex Assembly Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Fanconi Anemia Pathway	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester Artenimol
Diseases		Fanconi anemia
GWAS		Hair morphology traits ( 30166351) Homocysteine levels ( 23824729) Intraocular pressure ( 29617998 29785010 31959993 30054594) Low tan response ( 29739929) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Skin pigmentation traits ( 30166351)	Glycated hemoglobin levels ( 24647736) Household income (MTAG) ( 31844048) Mean corpuscular hemoglobin concentration ( 20139978) Mean corpuscular volume ( 29403010) Red blood cell count ( 29403010) Subcutaneous adipose tissue ( 22589738)
Interacting Genes		48 interacting genes: AKT1 ALDOA ATP5F1B ATR AURKA AZIN1 BRCA1 CAPN1 CCT3 CD79A CDK1 CENPE DAXX DDX39B DNAJB1 DUS4L ENO1 FANCC FANCE FANCF FANCG GNB2 HES1 HPRT1 HSP90AA1 IFIT3 IKBKB KRT1 LIPG MKNK1 MX1 NAMPT NUB1 PRKAA1 PRPF31 PSMA5 RPL18 SGK1 SMARCA4 SMARCC1 SMARCD3 SNX5 SPTAN1 TAF10 TCERG1 TCP1 TPT1 ZNF24	14 interacting genes: EIF2B2 FANCA HNRNPA0 HSPA8 LNX2 MAPK6 MIPOL1 PAFAH1B2 RAF1 SH3BP4 VAV2 VHL XRCC6 ZNRD2
Entrez ID		2175	7203
HPRD ID		06186	08969
Ensembl ID		ENSG00000187741	ENSG00000163468
Uniprot IDs		O15360	B3KX11 P49368 Q59H77
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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