FANCA and AZIN1

Number of citations of the paper that reports this interaction (PubMedID 14499622)
12

Data Source:
BioGRID (two hybrid)

		FANCA	AZIN1
Description		FA complementation group A	antizyme inhibitor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Ornithine Decarboxylase Activity Protein Binding Ornithine Decarboxylase Activator Activity
	Biological Process	DNA Repair Male Meiotic Nuclear Division Male Gonad Development Female Gonad Development Interstrand Cross-link Repair Regulation Of Cell Proliferation Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Regulation Of DNA-binding Transcription Factor Activity Protein-containing Complex Assembly Regulation Of CD40 Signaling Pathway	Regulation Of Cellular Amino Acid Metabolic Process Putrescine Biosynthetic Process From Ornithine Negative Regulation Of Protein Catabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Polyamine Transmembrane Transport
Pathways		Fanconi Anemia Pathway	Regulation of ornithine decarboxylase (ODC)
Drugs
Diseases		Fanconi anemia
GWAS		Hair morphology traits ( 30166351) Homocysteine levels ( 23824729) Intraocular pressure ( 29617998 29785010 31959993 30054594) Low tan response ( 29739929) Red vs. brown/black hair color ( 30531825) Rosacea symptom severity ( 29771307) Skin pigmentation traits ( 30166351)	Airway imaging phenotypes ( 26030696) Granulocyte count ( 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Neutrophil count ( 27863252) QT interval ( 24952745) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		48 interacting genes: AKT1 ALDOA ATP5F1B ATR AURKA AZIN1 BRCA1 CAPN1 CCT3 CD79A CDK1 CENPE DAXX DDX39B DNAJB1 DUS4L ENO1 FANCC FANCE FANCF FANCG GNB2 HES1 HPRT1 HSP90AA1 IFIT3 IKBKB KRT1 LIPG MKNK1 MX1 NAMPT NUB1 PRKAA1 PRPF31 PSMA5 RPL18 SGK1 SMARCA4 SMARCC1 SMARCD3 SNX5 SPTAN1 TAF10 TCERG1 TCP1 TPT1 ZNF24	6 interacting genes: ABCC2 ADSS1 CDKN2A FANCA FANCC KHDRBS1
Entrez ID		2175	51582
HPRD ID		06186	07443
Ensembl ID		ENSG00000187741	ENSG00000155096
Uniprot IDs		O15360	A0A024R9C7 B3KTF6 O14977
PDB IDs			4ZGZ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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