TXLNA and MED4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, proximity labelling technology, affinity chromatography technology)

		TXLNA	MED4
Description		taxilin alpha	mediator complex subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex
	Molecular Function	Protein Binding Syntaxin Binding	Transcription Coregulator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Exocytosis Cytokine-mediated Signaling Pathway B Cell Activation	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated
Pathways		Other interleukin signaling	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)
Interacting Genes		52 interacting genes: AZI2 BRCA1 BTF3 BTF3L4 CBY2 CCDC136 CCHCR1 CDR2 CEP44 CEP57L1 CEP63 DEUP1 DTNB EIF4ENIF1 GOLGA2 GORASP2 HAUS3 HYPK IKBKG KANK2 KRT13 KRT15 KRT20 KRT31 KRT38 KRT40 LCA5 MBIP MED4 MEOX1 MEOX2 NACA NDC80 NMI NSMCE2 NUP62 PPFIA1 RCOR3 RINT1 SMARCE1 STMN2 STX1A STX3 STX4 TCL1A TFIP11 TNIP1 TP53BP2 TXLNB USHBP1 VPS52 WASHC3	33 interacting genes: AMOT AP2M1 ATF7IP C1orf216 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD HAUS1 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED30 MED9 NDE1 PCBD2 PUM2 SDCBP SDCBP2 SGF29 SMARCD1 SMARCE1 SSX3 TLE5 TNFAIP8 TXLNA USHBP1 WDTC1
Entrez ID		200081	29079
HPRD ID		09408	16145
Ensembl ID		ENSG00000084652	ENSG00000136146
Uniprot IDs		P40222	A0A024RDY7 Q9NPJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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