ARID2 and NFYC

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		ARID2	NFYC
Description		AT-rich interaction domain 2	nuclear transcription factor Y subunit gamma
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane	Nuclear Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Heart Morphogenesis Nucleosome Disassembly Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Migration Homeostatic Process Embryonic Organ Development Cardiac Muscle Cell Proliferation Coronary Artery Morphogenesis Positive Regulation Of Double-strand Break Repair Via Homologous Recombination	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Protein Folding Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Chronotype ( 30696823) Hippocampal atrophy ( 19668339) Intelligence (MTAG) ( 29326435) Morning person ( 30696823) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglycerides ( 30275531)	Airway obstruction (FEV1/FVC<70%) in never smokers ( 30845926) Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers ( 30845926) Depressive and manic episodes in bipolar disorder ( 26297903) Platelet count ( 21507922)
Interacting Genes		6 interacting genes: ANO6 CCNA1 NFYC SMARCA4 SMARCE1 TSC22D2	26 interacting genes: ADNP2 ARID2 ATF6 ATF6B BICRA BICRAL CIC CSN2 DST GAPDH LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP USF3 ZDHHC17
Entrez ID		196528	4802
HPRD ID		16505	05633
Ensembl ID		ENSG00000189079	ENSG00000066136
Uniprot IDs		Q68CP9	Q13952
PDB IDs			1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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