NFYC and TAF11

Number of citations of the paper that reports this interaction (PubMedID 11689552)
22

Data Source:
BioGRID (pull down)

		NFYC	TAF11
Description		nuclear transcription factor Y subunit gamma	TATA-box binding protein associated factor 11
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Factor Complex	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Protein Folding Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II Positive Regulation By Host Of Viral Transcription RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Airway obstruction (FEV1/FVC<70%) in never smokers ( 30845926) Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers ( 30845926) Depressive and manic episodes in bipolar disorder ( 26297903) Platelet count ( 21507922)
Interacting Genes		26 interacting genes: ADNP2 ARID2 ATF6 ATF6B BICRA BICRAL CIC CSN2 DST GAPDH LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP USF3 ZDHHC17	28 interacting genes: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 H3-4 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR
Entrez ID		4802	6882
HPRD ID		05633	15980
Ensembl ID		ENSG00000066136	ENSG00000064995
Uniprot IDs		Q13952	Q15544
PDB IDs		1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS	1BH8 1BH9 6MZD 6MZL
Enriched GO Terms of Interacting Partners?
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