NFYC and TAF6

Number of citations of the paper that reports this interaction (PubMedID 11689552)
22

Data Source:
BioGRID (pull down)

		NFYC	TAF6
Description		nuclear transcription factor Y subunit gamma	TATA-box binding protein associated factor 6
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Factor Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex MLL1 Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Protein Folding Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	Chromatin Organization DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process SnRNA Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Airway obstruction (FEV1/FVC<70%) in never smokers ( 30845926) Airway obstruction (FEV1/FVC<lower limit of normal) in never smokers ( 30845926) Depressive and manic episodes in bipolar disorder ( 26297903) Platelet count ( 21507922)	Coronary artery disease ( 29212778)
Interacting Genes		26 interacting genes: ADNP2 ARID2 ATF6 ATF6B BICRA BICRAL CIC CSN2 DST GAPDH LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP USF3 ZDHHC17	23 interacting genes: AHR APP CIITA GTF2E1 H3-4 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9
Entrez ID		4802	6878
HPRD ID		05633	11807
Ensembl ID		ENSG00000066136	ENSG00000106290
Uniprot IDs		Q13952	A4D299 P49848
PDB IDs		1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS	5FUR 6F3T 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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