DTX3 and USP21

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		DTX3	USP21
Description		deltex E3 ubiquitin ligase 3	ubiquitin specific peptidase 21
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity NEDD8-specific Protease Activity Thiol-dependent Ubiquitinyl Hydrolase Activity Metal Ion Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Ubiquitin-dependent Protein Catabolic Process Histone Deubiquitination Protein Deubiquitination Neuron Projection Development Positive Regulation Of Transcription, DNA-templated
Pathways			TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		25 interacting genes: DTX1 DTX2 RNF141 RNF38 TRAF4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP ZDHHC17	54 interacting genes: ATXN3 AURKA BAP1 BRCA2 CBL CBLC DTX3 ESPL1 EXOSC10 FOXM1 H2AC18 ISG15 JOSD1 KRT40 LRSAM1 MAPK3 MPP1 NANOG OTUB1 OTUB2 PCGF6 RBCK1 RNF144A RNF185 SENP3 SENP8 SLF1 STAMBP SYNE1 TP53 TRAF6 TRIM23 TRIM5 TRIM54 TRIM63 TRIM8 TRIM9 UBC UBE2S UCHL1 UCHL3 USP14 USP15 USP2 USP20 USP28 USP33 USP4 USP51 USP7 USP8 WDR47 YOD1 ZNF350
Entrez ID		196403	27005
HPRD ID		16842	05291
Ensembl ID		ENSG00000178498	ENSG00000143258
Uniprot IDs		A0A024RB96 Q8N9I9	Q9UK80
PDB IDs			2Y5B 3I3T 3MTN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?