DTX3 and DTX1

Number of citations of the paper that reports this interaction (PubMedID 11226752)
25

Data Source:
HPRD (two hybrid)

		DTX3	DTX1
Description		deltex E3 ubiquitin ligase 3	deltex E3 ubiquitin ligase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Notch Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Transcription, DNA-templated Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Notch Signaling Pathway Regulation Of Notch Signaling Pathway Glial Cell Differentiation Protein Ubiquitination Negative Regulation Of T Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Nucleic Acid-templated Transcription Cellular Response To Leukemia Inhibitory Factor
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS			Body mass index ( 26426971) Coffee consumption ( 29367735) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		25 interacting genes: DTX1 DTX2 RNF141 RNF38 TRAF4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP ZDHHC17	20 interacting genes: DEFA5 DTX2 DTX3 DTX3L EP300 G3BP1 GRB2 ITCH MAP3K1 NOTCH1 NOTCH2 TAX1BP3 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2N UBE2U
Entrez ID		196403	1840
HPRD ID		16842	03991
Ensembl ID		ENSG00000178498	ENSG00000135144
Uniprot IDs		A0A024RB96 Q8N9I9	Q86Y01
PDB IDs
Enriched GO Terms of Interacting Partners?
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