RNF115 and RAD23A

Number of citations of the paper that reports this interaction (PubMedID 22315970)
11

Data Source:
BioGRID (two hybrid)

		RNF115	RAD23A
Description		ring finger protein 115	RAD23 homolog A, nucleotide excision repair protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Nucleotide-excision Repair Viral Process Protein Deubiquitination Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Breast cancer ( 25751625 29059683)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		31 interacting genes: AKT1 APP ATN1 CDK10 CST3 DAZAP2 DOCK4 EGFR FOLR3 HRAS IGHA1 MDM4 MFAP4 NFKBIA RAB7A RAD23A RPL18A TTR UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2I UBE2N UBE2W USP9X VCP ZNRD2	53 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CHEK1 CREBBP DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 HSPB1 IFIT3 IFIT5 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MPG NEDD8 NGLY1 PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RNF115 RNF32 RPN1 SMURF1 SQSTM1 TRAF2 TRAF5 TRIM54 TRIP6 UBB UBC UBE3A UBE4B UBL7 UBQLN4 USP25 VAV2 XPC ZBTB44 ZBTB8A
Entrez ID		27246	5886
HPRD ID		18328	07191
Ensembl ID		ENSG00000265491	ENSG00000179262
Uniprot IDs		Q9Y4L5	A0A024R7G8 A8K1J3 P54725
PDB IDs			1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ 5XBO
Enriched GO Terms of Interacting Partners?
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