DNMT3B and HDAC2

  • Number of citations of the paper that reports this interaction (PubMedID 23708667)
  • 38
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

DNMT3B

HDAC2

Description DNA methyltransferase 3 beta histone deacetylase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Inflammatory bowel disease ( 23128233)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Nicotine dependence ( 28972577)
  • Prostate cancer ( 29892016)
  • Pulse pressure ( 27841878 30578418)
  • Total cholesterol levels ( 30275531)
  • Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)
  • Metabolite levels ( 23823483)
Interacting Genes 38 interacting genes: BAZ2A CBX1 CBX3 CBX5 CMTM6 CUL4B DDB1 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 H3C1 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS1 ZBTB18 106 interacting genes: ANTXR1 APPL1 ARID4A AURKA BCL11A BRCA1 BRMS1 BRMS1L BUB3 CABIN1 CDC20 CDH1 CDKN1A CDYL CHD3 CHFR CIR1 CSNK2A1 CSNK2A2 CTBP1 CYTOR DAXX DDX20 DMAP1 DNMT1 DNMT3B EED EID2 FKBP3 FOXO3 FTCD FYN GATA3 H2AC1 H2AC20 H2BC21 H3-4 H3C1 HDAC1 HDAC10 HDAC7 HIF1A HIF1AN HOPX HUWE1 IFRD1 IKZF1 IKZF4 ING1 LAMA4 MAD1L1 MBD2 MBD3L2 MEN1 MTA1 MTA2 MXD1 NACC2 NRIP1 PA2G4 PADI4 PHB2 PHF21A PIAS4 PML PPARD PPP1R8 PTMA RBBP4 RBBP7 RBP1 RCOR1 RELA REV3L RFX5 RUNX3 SALL1 SAP30 SETDB1 SIN3A SMAD2 SMARCA5 SMYD1 SNW1 SP1 SP3 SPEN SS18L1 STAT3 STK25 SUMO2 SUV39H1 SYK TFCP2 THRA THRB TNS4 TOP2A TOP2B TP53 TREML2 USP4 VHL YY1 ZBTB16 ZNF461
Entrez ID 1789 3066
HPRD ID 04209 05521
Ensembl ID ENSG00000088305 ENSG00000196591
Uniprot IDs Q9UBC3 Q92769
PDB IDs 3FLG 3QKJ 5CIU 5NR3 5NRR 5NRS 5NRV 5NV0 5NV2 5NV7 5NVO 3MAX 4LXZ 4LY1 5IWG 5IX0 6G3O
Enriched GO Terms of Interacting Partners?
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