DNMT3B and HELLS

  • Number of citations of the paper that reports this interaction (PubMedID 17967891)
  • 53

DNMT3B

HELLS

Description DNA methyltransferase 3 beta helicase, lymphoid specific
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Inflammatory bowel disease ( 23128233)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Nicotine dependence ( 28972577)
  • Prostate cancer ( 29892016)
  • Pulse pressure ( 27841878 30578418)
  • Total cholesterol levels ( 30275531)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Response to (pegylated) interferon in chronic hepatitis B ( 30715261)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Interacting Genes 38 interacting genes: BAZ2A CBX1 CBX3 CBX5 CMTM6 CUL4B DDB1 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 H3C1 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS1 ZBTB18 5 interacting genes: APP DNMT1 DNMT3B E2F3 HDAC1
Entrez ID 1789 3070
HPRD ID 04209 07232
Ensembl ID ENSG00000088305 ENSG00000119969
Uniprot IDs Q9UBC3 A0A087WSW7 A0A0B4J1V9 F6XU50 Q0VGL2 Q76H82 Q9NRZ9
PDB IDs 3FLG 3QKJ 5CIU 5NR3 5NRR 5NRS 5NRV 5NV0 5NV2 5NV7 5NVO
Enriched GO Terms of Interacting Partners?
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