DNMT3B and SMC2

  • Number of citations of the paper that reports this interaction (PubMedID 15148359)
  • 46
  • Data Source:
  • BioGRID (biochemical, pull down)

DNMT3B

SMC2

Description DNA methyltransferase 3 beta structural maintenance of chromosomes 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Inflammatory bowel disease ( 23128233)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Lymphocyte counts ( 27863252)
  • Lymphocyte percentage of white cells ( 27863252)
  • Nicotine dependence ( 28972577)
  • Prostate cancer ( 29892016)
  • Pulse pressure ( 27841878 30578418)
  • Total cholesterol levels ( 30275531)
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Basal cell carcinoma ( 31174203)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Orofacial clefts (maternal alcohol consumption interaction) ( 21618603)
  • Pancreatic cancer ( 29422604)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Sensorimotor dexterity ( 31596458)
Interacting Genes 38 interacting genes: BAZ2A CBX1 CBX3 CBX5 CMTM6 CUL4B DDB1 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 H3C1 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS1 ZBTB18 9 interacting genes: ABCC5 DISC1 DNMT3B ERP44 GULP1 LIG4 NCAPD2 SMC4 TRAF3IP1
Entrez ID 1789 10592
HPRD ID 04209 09277
Ensembl ID ENSG00000088305 ENSG00000136824
Uniprot IDs Q9UBC3 A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1
PDB IDs 3FLG 3QKJ 5CIU 5NR3 5NRR 5NRS 5NRV 5NV0 5NV2 5NV7 5NVO 4U4P
Enriched GO Terms of Interacting Partners?
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