DES and SYNC

Number of citations of the paper that reports this interaction (PubMedID 11694502)
23

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		DES	SYNC
Description		desmin	syncoilin, intermediate filament protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intermediate Filament Fascia Adherens Intercalated Disc Z Disc Neuromuscular Junction Sarcolemma Intermediate Filament Cytoskeleton Extracellular Exosome Cardiac Myofibril	Cytosol Intermediate Filament Z Disc Neuromuscular Junction Sarcolemma Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Muscle Contraction Cytoskeleton Organization Regulation Of Heart Contraction Muscle Filament Sliding Intermediate Filament Organization	Intermediate Filament-based Process
Pathways		Striated Muscle Contraction
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Scapuloperoneal myopathy (SPM) Dilated cardiomyopathy (DCM)
GWAS		Resting heart rate ( 27798624)
Interacting Genes		27 interacting genes: AURKB BRCA1 CAPN1 CRYAB DDX10 DSP EHHADH HSPB1 ITSN1 MAPKAPK2 NEB NEFL PKD1 PLEKHA5 PPP1R18 ROCK1 S100A1 S100B SHBG SPTAN1 SYNC SYNM TRIM55 TRIM63 TRIM7 UBE2I VIM	2 interacting genes: DES DTNA
Entrez ID		1674	81493
HPRD ID		00514	18134
Ensembl ID		ENSG00000175084	ENSG00000162520
Uniprot IDs		P17661 Q53SB5	Q9H7C4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?