AP1B1 and BUB1

Number of citations of the paper that reports this interaction (PubMedID 12419313)
12

Data Source:
HPRD (two hybrid)

		AP1B1	BUB1
Description		adaptor related protein complex 1 subunit beta 1	BUB1 mitotic checkpoint serine/threonine kinase
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleoplasm Cytosol Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Protein Phosphorylation Apoptotic Process Regulation Of Sister Chromatid Cohesion Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		22 interacting genes: AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A MTNR1B NTRK2 PIP5K1C PRKDC SHBG SLC2A8 SMAD2	18 interacting genes: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB3 CDC20 CDK1 CRK EIF4EBP1 FBXO7 HDAC1 KNL1 PLK1 RAE1 RDH12 SVIL
Entrez ID		162	699
HPRD ID		02541	03907
Ensembl ID		ENSG00000100280	ENSG00000169679
Uniprot IDs		Q10567	B4DYG2 O43683
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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