AP1B1 and BUB1B

Number of citations of the paper that reports this interaction (PubMedID 12419313)
12

Data Source:
HPRD (two hybrid)

		AP1B1	BUB1B
Description		adaptor related protein complex 1 subunit beta 1	BUB1 mitotic checkpoint serine/threonine kinase B
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Chromosome Outer Kinetochore Anaphase-promoting Complex Cytoplasm Microtubule Organizing Center Spindle Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Mitotic Cell Cycle Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Anaphase-promoting Complex-dependent Catabolic Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Inactivation of APC/C via direct inhibition of the APC/C complex Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Cdc20:Phospho-APC/C mediated degradation of Cyclin A APC/C:Cdc20 mediated degradation of mitotic proteins APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Pancreatic cancer ( 25086665)	Chronic lymphocytic leukemia ( 28165464 24292274)
Interacting Genes		22 interacting genes: AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A MTNR1B NTRK2 PIP5K1C PRKDC SHBG SLC2A8 SMAD2	26 interacting genes: ANAPC7 AP1B1 AP2B1 AP3B1 AP4B1 APC BRCA2 BUB3 CCNA2 CDC16 CDC20 CDC27 CENPE COMMD4 DNMBP FBXO7 FZR1 HDAC1 KNL1 MAP3K4 PELI1 PLK1 RIPK3 SNCG TP73 TRIP13
Entrez ID		162	701
HPRD ID		02541	04176
Ensembl ID		ENSG00000100280	ENSG00000156970
Uniprot IDs		Q10567	O60566
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	2WVI 3SI5 4GGD 5JJA 5K6S 5KHU 5LCW 5SWF
Enriched GO Terms of Interacting Partners?
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