AP1B1 and ARF5

Number of citations of the paper that reports this interaction (PubMedID 11926829)
15

Data Source:
HPRD (in vitro, in vivo)

		AP1B1	ARF5
Description		adaptor related protein complex 1 subunit beta 1	ADP ribosylation factor 5
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle-mediated Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Pancreatic cancer ( 25086665)	Type 2 diabetes ( 23532257)
Interacting Genes		22 interacting genes: AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP KIF13A MTNR1B NTRK2 PIP5K1C PRKDC SHBG SLC2A8 SMAD2	12 interacting genes: AASS AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 GGA1 GORAB IKBKG PIP5K1A RAB11A RAB11FIP3
Entrez ID		162	381
HPRD ID		02541	00055
Ensembl ID		ENSG00000100280	ENSG00000004059
Uniprot IDs		Q10567	A4D0Z3 P84085
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	2B6H
Enriched GO Terms of Interacting Partners?
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