CTSB and STK11

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 5
  • Data Source:
  • BioGRID (two hybrid)

CTSB

STK11

Description cathepsin B serine/threonine kinase 11
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • General risk tolerance (MTAG) ( 30643258)
  • Leprosy ( 27976721)
  • Parkinson's disease ( 28892059)
  • Parkinson's disease in GBA mutation carriers ( 31755958)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Triglyceride levels ( 29083408)
  • Triglycerides ( 30275531)
  • Asthma (childhood onset) ( 31036433)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Lymphocyte counts ( 27863252)
  • Psychosis in Alzheimer's disease ( 22005930)
Interacting Genes 36 interacting genes: A2M ACAN ADAMTSL4 ANXA2 ANXA7 APOE APP BAG6 BGLAP CDKN1A CST3 CST7 CSTA CSTB CTSD FAM118B HNRNPD HSPB2 IGF1 INS MARCKS MTDH PARP1 PLAU REN RGS2 S100A10 SERPINB13 SLPI SPHK1 SPINT2 SPRY2 SRPX2 STK11 UBQLN4 XRN1 113 interacting genes: ABCB5 ADIPOR1 AKT1 APP ARAF ARG2 ARNT ATM AURKA BCAS3 BECN1 BRAF CAB39 CALM2 CBLC CCND2 CCNE1 CD44 CDC37 CDK4 CDK6 CDKN2A CDKN2B CDKN2C CFL2 CRY2 CTSB CYP17A1 D2HGDH DACH1 EEF1A2 EPHA2 ERBB2 ERLEC1 ETV4 FAIM2 FGFR4 FZR1 GLIS2 GNPDA1 GRM1 HERC2 HGF HIF1A KAT2A KDELR2 KLK7 LATS2 LYPD3 MAP2K3 MAP2K5 MAP2K6 MAP3K5 MAPK14 MAPRE1 MARK1 MARK2 MARK4 MDM2 MET MOB4 MOCS2 MT-ND2 MYC NAT2 NF2 PARD3 PDGFRA PDXP PHF23 PIK3CA PLD3 PRKAA1 PRKAA2 PRKACA PRSS50 PTEN RASSF1 RHOBTB2 RPS6KA3 RPS6KA5 RPS6KB1 S100A14 SEPTIN9 SERPINB5 SIK1 SIRT1 SMAD1 SMARCA4 SNRK SOX4 SPDEF ST14 STK11IP STK24 STRADA STRADB TBC1D23 TEAD2 TERT THOP1 THRSP TNFRSF1A TNIP2 TP53 TRIM25 TSG101 TUBA1A TUBB4A UBE2D2 VPS72 WT1 YWHAG
Entrez ID 1508 6794
HPRD ID 00287 03740
Ensembl ID ENSG00000164733 ENSG00000118046
Uniprot IDs A0A024R374 B4DMY4 P07858 Q5HYG5 A0A0S2Z4D1 Q15831
PDB IDs 1CSB 1GMY 1HUC 1PBH 2IPP 2PBH 3AI8 3CBJ 3CBK 3K9M 3PBH 5MBL 5MBM 6AY2 2WTK 4ZDR 5WXN
Enriched GO Terms of Interacting Partners?
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