EFTUD2 and ARPC3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		EFTUD2	ARPC3
Description		elongation factor Tu GTP binding domain containing 2	actin related protein 2/3 complex subunit 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filamentous Actin Site Of Double-strand Break Growth Cone Leading Edge Extracellular Exosome
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine	Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Ephrin Receptor Signaling Pathway Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Nerve Growth Factor Stimulus
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Asthma ( 31619474) Craniofacial microsomia ( 26853712)	Automobile speeding propensity ( 30643258) Bipolar disorder ( 31043756) Femoral neck bone mineral density ( 30172743)
Interacting Genes		12 interacting genes: ARPC3 CYFIP1 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 WBP4	21 interacting genes: ACTR3 ARAP1 ARPC4 BAG6 CDKN2B CETP EFTUD2 GOLGA2 HOXA3 LGALS4 LTA4H MAPK6 NRIP1 OTUD5 PRMT1 RPS4X THNSL2 WAS WASF2 WASHC4 WASL
Entrez ID		9343	10094
HPRD ID		04869	09175
Ensembl ID		ENSG00000108883	ENSG00000111229
Uniprot IDs		B3KX19 Q15029	O15145
PDB IDs		3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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