ASB6 and SH2B2

Number of citations of the paper that reports this interaction (PubMedID 15231829)
21

		ASB6	SH2B2
Description		ankyrin repeat and SOCS box containing 6	SH2B adaptor protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification	Signal Transduction Blood Coagulation Insulin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Intracellular Signal Transduction Antigen Receptor-mediated Signaling Pathway
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Type 2 diabetes ( 31049640)
Interacting Genes		5 interacting genes: APP FAM9B L3MBTL3 RNF41 SH2B2	22 interacting genes: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN MTDH NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID		140459	10603
HPRD ID		10673	16097
Ensembl ID		ENSG00000148331	ENSG00000160999
Uniprot IDs		F6TX30 Q9NWX5	O14492
PDB IDs			1Q2H
Enriched GO Terms of Interacting Partners?
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