CRK and MYLIP

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 22
  • Data Source:
  • BioGRID (two hybrid)

CRK

MYLIP

Description CRK proto-oncogene, adaptor protein myosin regulatory light chain interacting protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Cholesterol, total ( 24097068)
  • Diisocyanate-induced asthma ( 25918132)
  • Femoral neck bone mineral density ( 30172743)
  • LDL cholesterol ( 24097068 20864672 25961943)
  • LDL cholesterol levels ( 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Major depressive disorder ( 23377640)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Total cholesterol levels ( 28334899)
Interacting Genes 166 interacting genes: ABL1 ABL2 ANKZF1 ANLN ARHGAP17 ARHGAP32 ASAP1 ASAP3 ASCL4 ATF3 ATXN1 AVIL BATF3 BCAR1 BCR BEX5 BUB1 C1orf94 C4orf17 C6orf141 CBL CBLB CBLC CHTF18 CLNK CNDP2 CORO6 CRKL DAB1 DOCK1 DOCK3 DOK1 DOK2 DOK3 DOK4 DOK7 DPPA4 EFS EGFR ELK1 ELK3 EPHA3 EPHB2 EPHB3 EPHB6 EPS15 EPYC ERBB2 ERBB3 ERBB4 ESD EYA3 FASLG FER FGFR1 FLACC1 FLT1 FRS2 FSTL1 FYN GAB1 GABPB2 GAREM1 GRB2 HABP4 HSH2D IFT140 IGF1R IKZF3 INO80E INSR IRS1 IRS2 IRS4 ISL1 KCTD13 KCTD17 KDR KHDRBS1 KIT KLF15 KLHL20 LASP1 LHX8 LNX2 MAGEC3 MAP4K1 MAP4K5 MAPK4 MAPK8 MICAL1 MNDA MPG MYLIP MYOZ2 NCK1 NEDD9 NTRK1 NUFIP2 OFCC1 PAFAH1B2 PDGFRA PDGFRB PHC2 PIK3R1 PIK3R2 PIK3R3 PLSCR1 POT1 PPFIBP2 PPP1CA PRKACA PRRC2B PRRG2 PSMC1 PSMC6 PTK2 PTK2B PTPN1 PTPN4 PTPRH PTTG1 PXN RAB2B RAPGEF1 REPS1 RET RIN3 RTCB RYBP SASH1 SAXO1 SEMA4D SEPTIN6 SETD9 SH2D2A SH3BP1 SHB SHC1 SOCS1 SOCS6 SOS1 SPRR2A STAT4 STAT5A STAT5B STRN4 SYN1 TCAP TDG TERF2IP TM4SF19 TP53 TP53BP2 TUBA1C TWIST2 USP53 VAC14 VAV1 WASF1 WDR83 WEE1 XPO1 ZAP70 ZKSCAN7 ZNF557 18 interacting genes: AR CNPY2 CRK DAPP1 KDM1A LNX2 LRP8 MIPOL1 MTAP MYL12B RASSF5 SRPK2 TSC22D4 UBE2D2 UBE2D3 UBE2D4 UBE2N VLDLR
Entrez ID 1398 29116
HPRD ID 01267 17621
Ensembl ID ENSG00000167193 ENSG00000007944
Uniprot IDs A0A0S2Z3K9 A0A0S2Z3Q4 L7RT18 P46108 Q5TIA5 Q8WY64
PDB IDs 1JU5 2DVJ 2EYV 2EYW 2EYX 2EYY 2EYZ 2MS4 5UL6 6ATV 2YHN 2YHO
Enriched GO Terms of Interacting Partners?
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