MYLIP and MTAP

  • Number of citations of the paper that reports this interaction (PubMedID 12826659)
  • 20
  • Data Source:
  • HPRD (in vitro, two hybrid)

MYLIP

MTAP

Description myosin regulatory light chain interacting protein methylthioadenosine phosphorylase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Cholesterol, total ( 24097068)
  • Diisocyanate-induced asthma ( 25918132)
  • Femoral neck bone mineral density ( 30172743)
  • LDL cholesterol ( 24097068 20864672 25961943)
  • LDL cholesterol levels ( 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Major depressive disorder ( 23377640)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Total cholesterol levels ( 28334899)
  • Adverse response to drug ( 30420678)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary heart disease ( 21606135)
  • Cutaneous nevi ( 19578365)
  • Diastolic blood pressure ( 28135244)
  • Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
  • Glycated hemoglobin levels ( 28898252)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Lung function in heavy smokers (low FEV1 vs high FEV1) ( 26423011)
  • Macular thickness ( 30535121)
  • Melanoma ( 21983787 28212542)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 30429480)
  • Pediatric bone mineral content (radius) ( 26041818)
  • Pulse pressure ( 28135244)
Interacting Genes 18 interacting genes: AR CNPY2 CRK DAPP1 KDM1A LNX2 LRP8 MIPOL1 MTAP MYL12B RASSF5 SRPK2 TSC22D4 UBE2D2 UBE2D3 UBE2D4 UBE2N VLDLR 6 interacting genes: CDC25A CENPH FOLH1 LYRM1 MYLIP RELB
Entrez ID 29116 4507
HPRD ID 17621 01134
Ensembl ID ENSG00000007944 ENSG00000099810
Uniprot IDs Q5TIA5 Q8WY64 A0A384ME80 Q13126
PDB IDs 2YHN 2YHO 1CB0 1CG6 1K27 1SD1 1SD2 3LN5 3OZC 3OZD 3OZE 5EUB 5TC5 5TC6 5TC7 5TC8 6DYZ 6DZ0 6DZ2 6DZ3
Enriched GO Terms of Interacting Partners?
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