CKS2 and TSC22D4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CKS2	TSC22D4
Description		CDC28 protein kinase regulatory subunit 2	TSC22 domain family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex SCF Ubiquitin Ligase Complex	Nucleus
	Molecular Function	Chromatin Binding Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Meiosis I Regulation Of Mitotic Cell Cycle Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Platelet count ( 27863252)
Interacting Genes		14 interacting genes: BLZF1 CCNA1 CCNB2 CDC37 CDK1 CKS1B EEF1A1 GRB2 HSP90AA1 LDHB SSBP1 TSC22D4 UNC119 VTN	54 interacting genes: ABLIM1 AIFM1 APIP BLZF1 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TSC22D1 TSPOAP1 UBLCP1 ZBTB24 ZMYND10 ZNF580
Entrez ID		1164	81628
HPRD ID		00300	18231
Ensembl ID		ENSG00000123975	ENSG00000166925
Uniprot IDs		P33552	B4DKI8 Q9Y3Q8
PDB IDs		1CKS 4Y72 4YC3 5HQ0 5LQF 6GU2 6GU3 6GU4 6GU6 6GU7
Enriched GO Terms of Interacting Partners?
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