TSC22D4 and AIFM1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		TSC22D4	AIFM1
Description		TSC22 domain family member 4	apoptosis inducing factor mitochondria associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	DNA Binding Protein Binding NAD(P)H Oxidase Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated	Response To Ischemia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Chromosome Condensation Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Protein Import Into Mitochondrial Intermembrane Space Neuron Apoptotic Process Oxidation-reduction Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hydrogen Peroxide Cellular Response To Estradiol Stimulus Cellular Response To Nitric Oxide Cellular Response To Oxygen-glucose Deprivation Response To L-glutamate Regulation Of Apoptotic DNA Fragmentation Cellular Response To Aldosterone
Pathways
Drugs			Flavin adenine dinucleotide MCC
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Platelet count ( 27863252)	Bipolar disorder ( 31043756)
Interacting Genes		54 interacting genes: ABLIM1 AIFM1 APIP BLZF1 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TSC22D1 TSPOAP1 UBLCP1 ZBTB24 ZMYND10 ZNF580	12 interacting genes: CASP3 DCAF7 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP
Entrez ID		81628	9131
HPRD ID		18231	02161
Ensembl ID		ENSG00000166925	ENSG00000156709
Uniprot IDs		B4DKI8 Q9Y3Q8	E9PMA0 O95831
PDB IDs			1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI
Enriched GO Terms of Interacting Partners?
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